Pulmonary Toxicology and Lung Disease Events- Seminars, Pilot Projects and Community Outreach and Education

Seminar Speakers Associated with the Pulmonary Toxicology and Lung Disease Research Core

Date	Speaker	Institution	Topic
05/17/01	Bob Burghardt Host: Lantz	Texas A & M University	Espying Cellular Injury on the Micrometer Scale
04/18/02	Andrij Holian Host: Lantz	University of Montana	Alveolar Macrophages and lung Injury
11/21/02	David Hinton Host: Lantz	Duke University	Analysis of Chemical Carcinogenesis in Fish Models
01/17/03	Peter Ward Host: Burgess	University of Michigan	Regulation of Cytokine-mediated Lung Injury
01/15/04	Judy Zelikoff Host: Lantz	New York University	Air particulates and immune response
02/19/04	Bruce Pitt Host: Lantz	University of Pittsburgh	Imaging, lung endothelium, NO and oxygen radicals
04/15/04	Dori Germolec Host: Lantz	NIEHS	Arsenic

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Pilot Projects
The Pilot Projects Program has been invaluable in establishing and expanding this core. Since this Core was originally established in 2000, Pilot Projects have been used to recruit new members to the Research Core. These projects were awarded to Drs. Riley, Vercelli, McDonagh, and Boitano. (Dr. Vercelli’s research interests do not currently include environmental toxicology and she has been dropped from the membership.) Expanding the Research Core in this manner has allowed the Center to target investigators who had not previously been involved in environmental health research. The addition of these new members has established a critical mass of investigators that will maintain this as a viable Research Core. The inclusion of these new members has resulted in additional collaborative interactions among the Core and has resulted in several new funded and pending grants. Table XI.3 summarizes the Pilot Projects that have facilitated the interactive research for the Pulmonary Toxicology and Lung Disease Research Core.

Pilot Project Involvement of Core Members

Investigator	Year	Project Title (Resulting funding and publications)
Lantz	1998	Effect of Airborne Particulates on Development of Asthma (ADCRC; CA096281)
Burgess	1998	Serum Biomarkers of Lung Injury: A Longitudinal Analysis of Police (NIOSH matching funds; 2 publications)
Burgess	1999	Use of Pulmonary Macrophages as Biomarkers of Genotoxic Exposure (US Army; NIEHS Supplement, NIOSH ERC Pilot Project)
Lantz	2000	Role of IL-10 in Chronic Obstructive Pulmonary Disease (2 publications)
Burgess	2001	Use of cDNA microarray to evaluate alterations in gene expression in bronchoepithelial cells (P30 ES06694, Admin Supplement; P42 ES04940 CBPIR addition)
Riley	2001	Cell-based Biosensor Measurement of Airborne Particulate (DARPA, European Union, UA Water Quality, NSF, EPA, US Army grants; 6 publications)
Vercelli	2001	Gene-by-Environment Interactions in the Pathogenesis of Allergic Asthma
McDonagh	2002	Activation of the Systemic Inflammatory Response Following Inhalation of Airborne Particulate Matter (ADCRC; 1 publication)
Boitano	2003	Modeling the Alveolar Epithelium

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Community Outreach and Education
Members of the Research Core have been active in COEP. Several of the investigators have participated in the following.

• Presentation of data and development of research activities used in the Biology Project website at the University of Arizona (www.biology.arizona.edu/chh/).
• The annual summer Teacher Training Workshops sponsored by the Center, presenting general information on air pollution as well as relating their research
• Website information and support relative to air pollution and to arsenic effects on health, for the Tucson Water Collaboration
• Presentations to Sunnyside High School students using curricula developed by COEP staff for the IMPACTT program
• Dr. Burgess helped secure funding from EPA for an EMPACT (Environmental Monitoring for Public Access and Community Tracking) grant on air monitoring. A website was developed in concert with the SWEHSC Outreach program and the Pima County Department of Environmental Quality (www.airinfonow.com). This has allowed us to communicate with the public the effects of poor air quality on their health.

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