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Chemical Chromatin Interactions Events - Seminars, Meetings, Pilot Projects, and Community Outreach and Education


See also: Publications
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Seminars
SWEHSC Seminar Speakers during the past funding period with research interests commensurate with those of RC3 faculty include:

  • Dr. Harry Ischiropoulos (University of Pennsylvania) “Biological Significance and Clinical Relevance and Clinical Relevance of Protein Tyrosine Nitration”
  • Richard Caprioli (Vanderbilt University) “Profiling and Imaging of Peptides and Proteins in Tissues Using Mass Spectrometry”
  • On October 12, 2002, the Environmental Proteomics Research Core sponsored a workshop on "Proteomic Analysis of DNA-Protein Interactions." Speakers/participants included:
    • Dr. Liebler (former SWEHSC Director)
    • Dr. Kenneth Ramos (Texas A&M University) “Molecular Insights into Redox-Regulated Transcription”
    • Dr. Kathleen Dixon (University of Cincinnati) “Hyperphosphorylation of RPA-p34: RPA Phosphorylation and Protein Binding Affinity”
    • Dr. Ted Weinert (University of Arizona)” Mic1/Doc2 Contribute to Replication Stability”
    • Dr. Amy Ham (University of Arizona) “Et743 work with Dr. Hurley’s Laboratory”
    • Dr. Donato Romagnolo (SWEHSC RC3 investigator) “Estrogens and Breast Cancer: Regulation of the BACA1 Gene by Estrogen Thru Non-classical Mechanisms Requires a Functional p53 Pathway”.

    This meeting served as an informal means of assessing the advances and research challenges in identifying proteins that interact with specific gene sequences or DNA lesions.

Core Meetings
Dr. Monks was appointed Director of the Chemical-Chromatin Interactions RC on December 15th 2003. The first meeting of the RC was held on January 12th, 2004. Future meetings will be held on a regular (monthly/bimonthly) basis.

Pilot Project Involvement of Core Members
The Chemical-Chromatin Interactions Research Core has been competitive in obtaining pilot project funding from the SWEHSC.

Investigator Year Title
Romagnolo 1998 Molecular Regulation of Human BRCA-1 Gene (US DOD, RO1 ES009966)
Futscher 1998 The Role of P15 Gene Inactivation During Human Leukemogenesis (2 publications)
Romagnolo 2000 Genomic and Proteomic Fingerprints of Polycyclic Aromatic Hydrocarbons in Breast Cancer Cells (3
AZ Disease control grants)
Futscher 2001 Microarray Technology to Profile CpG Island Methylation in Cancer (R21/R33 CA091351)

Community Outreach and Education
RC3 members have participated in a variety of the COEP activities during this funding period. Past and present members supported COEP with presentations, web based information, and activities for students. Examples of Core member support for COEP are the following:

• Dr. Bowden was a Presenter for the Chemicals & Cancer Workshop, for BIOC 597c Current Topics for Biology Teachers: Poison, and for the Pollution & Public Health class.
• Dr. E. Jacobson answered a health-related question submitted through the COEP website. This answer is posted to the COEP website.
• Dr. Liebler, past member, supported various COEP endeavors as Center Director; specifically he was a presenter at the Society of Toxicology “Paracelsus Goes to School Teacher Workshop”, and at the Plants & Toxicology workshop for Tucson area teachers.
• Dr. Chen is currently sponsoring a high school student in her laboratory and was instrumental in connecting COEP with the University High School Research Program. In addition, Dr. Chen serves on the IAB for the SWEHSC outreach program.
• Dr. Futscher participated in the Med Start (1999 – 2003) and taught summer High School students about nucleic acids and the isolation of DNA
.

 


Southwest Environmental Health Sciences Center
University of Arizona College of Pharmacy, Room 244
PO Box 210207, Tucson, AZ, USA  85721-0207
swehsc-info@pharmacy.arizona.edu
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