Serum PCB profiles in Native Americans from Wisconsin based on region, diet, age, and gender: Implications for epidemiology studies

Author Name: 
Schaeffer, D. J., Dellinger, J. A., Needham, L. L. and Hansen, L. G.
Publication Date: 
Sunday, January 1, 2006
Private File Attachment: 
Description: 
Thirty-six (36) polychlorinated biphenyl (PCB) congeners were measured by gas chromatography isotope-dilution mass spectrometry (IDMS) in 314 serum samples from Native Americans in Wisconsin, Michigan and Minnesota. Five dietary groups were established based on the quantity and species of fish consumed and the waters from which the fish were caught. (Schaeffer, 2006) The five tribal groupings can be found in the Dellinger 2004 article. These were also used to have comparison with the data Schaeffer et al collected. In graph 1: there is a listing of every lake studied, the genus of every fish found inside the respective lakes and the average PCB count found in the fish. The human subjects height weight and gender were recorded. The congener profiles and studies of homologues were created. Various metrics were applied to the data to find patterns and pcb concentrations (ppb). Finally this study references DeCaprio, et. Al. in press, explaining that they used something called an “olytropic vector analysis to determine probable exposure sources from PCB profiles in the serum of Akwesasne Mohawks”. Those who are looking for a particular method of proof and large feature rich data set should read this article. Those who are beginners may find the literature of hard rowing and tough to use.