George Watts

Genomics Facility Core Co-Director
Key Personnel
Education: 

PhD, Pharmacology and Toxicology, University of Arizona 1998
BS, Chemistry, University of Delaware 1993

College Affiliations: 

College of Medicine

Research Interests: 

The Genomics Facility Core provides researchers with genomics services including sequencing, microarrays, and real time PCR along with support in sample preparation, experiment design, and data analysis.

Dr. Watts' own lab is working to improve clinical diagnosis of infection using next-gen sequencing. They are interested in providing more accurate and rapid diagnosis in clinical settings that are typically difficult to diagnose such as valley fever,

neutropenic fever, and diabetic foot ulcers.

 

Environmental Health Research & Expertise: 

As co-director of the Genomics Facility Core in the Center grant Dr. Watts over-sees daily operation of the laboratory staff, participates in future planning, and implement new technologies and techniques. He is also responsible for budgetary planning, billing, yearly reporting, generation of grant applications, and community outreach (both research and the lay public). Finally, and most importantly, he is the initial point of contact for researchers considering the Genomic Core’s services, assisting users in defining their research questions, in questions of sample preparation, quality control, and finally choosing an appropriate platform. He can also assist users in getting the data analysis need by pointing them to the resources available through the Biostatistics Core and helping to shape their expectations. He has developed microarray and sequencing capability within the Core and has been running the Genomics Core for 14 years. His research is heavily dependent on microarray and genomic applications thus giving him the experience of a user as well as provider of genomics technology and giving him the perspective of the researchers coming to the Core for assistance.

Select Publications

2015

Jandova, J., C. J. Mason, S. C. Pawar, and G. S. Watts, "Fn14 receptor promotes invasive potential and metastatic capacity of non-small lung adenocarcinoma cells through the up-regulation of integrin α6.", Neoplasma, vol. 62, issue 1, pp. 41-52, 2015. PubMed PMCID: PMC4455767  PMID: 25563366

2014

White, A. G., G. S. Watts, Z. Lu, M. M. Meza-Montenegro, E. A. Lutz, P. Harber, and J. L. Burgess, "Environmental arsenic exposure and microbiota in induced sputum.", Int J Environ Res Public Health, vol. 11, issue 2, pp. 2299-313, 2014 Feb 21. PubMed PMCID: PMC3945600  PMID: 24566055
Garbe, J. C., L. Vrba, K. Sputova, L. Fuchs, P. Novak, A. R. Brothman, M. Jackson, K. Chin, M. A. LaBarge, G. Watts, et al., "Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.", Cell Cycle, vol. 13, issue 21, pp. 3423-35, 2014. PubMed PMCID: PMC4613853  PMID: 25485586
Rankin, T. M., N. A. Giovinco, D. J. Cucher, G. Watts, B. Hurwitz, and D. G. Armstrong, "Three-dimensional printing surgical instruments: are we there yet?", J Surg Res, vol. 189, issue 2, pp. 193-7, 2014 Jun 15. PubMed PMCID: PMC4460996  PMID: 24721602

2013

Cyr, A. R., K. E. Brown, M. L. McCormick, M. C. Coleman, A. J. Case, G. S. Watts, B. W. Futscher, D. R. Spitz, and F. E. Domann, "Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes.", Redox Biol, vol. 1, pp. 172-7, 2013. PubMed PMCID: PMC3757676  PMID: 24024150