A. Jay Gandolfi

Member
Research Focus Group Membership: 
Research Focus Group 1
Education: 

Ph.D., Oregon State University 1972

College Affiliations: 

College Of Pharmacy

Research Interests: 

A. Jay Gandolfi, PhD, is professor emeritus in the Department of Pharmacology and Toxicology and the former associate dean for research and graduate studies (1999-2012). Dr. Gandolfi taught drug disposition in both PharmD and the graduate student curricula. He directed the Graduate Council and was director of the NIEHS Superfund Program from 1999-2012.

Dr. Gandolfi's research interests were in the disposition and toxicology of drugs (e.g., anesthetics) and environmental chemicals (e.g., arsenicals) and the development of in vivo and in vitro models for studying mechanisms of toxicity. 

Dr. Gandolfi joined the University of Arizona in 1978 and had appointments in the College of Medicine (Anesthesiology, Pharmacology) and the College of Pharmacy (Pharmacology and Toxicology). He received the College of Pharmacy's Findlay E. Russell MD, PhD, Distinguished Citizen Award in 2007 for services to the college and university.

Environmental Health Research & Expertise: 

Dr. Gandolfi directed toxicology research projects at the University of Arizona since 1978.  His research interests are in the toxicity of halogenated hydrocarbons and metals with an emphasis on hepatic and renal systems.  He was also active in developing in vitro toxicity models (e.g. precision cut tissue slice culture) and the disposition of xenobiotics.  He was part of the original team to coordinate and receive funding for the NIEHS Toxicology Center and was a research focus group leader from 1994 – 2012.  He directed the NIEHS Superfund Program and was cofounder of the Arizona-Mexico Binational Center.

Select Publications

2015

Recio-Vega, R., T. Gonzalez-Cortes, E. Olivas-Calderon, C. R Lantz, J. A Gandolfi, and C. Gonzalez- De Alba, "In utero and early childhood exposure to arsenic decreases lung function in children.", J Appl Toxicol, vol. 35, issue 4, pp. 358-66, 2015 Apr. PubMed PMCID: PMC4750377  PMID: 25131850
Ramirez-Andreotta, M. D., M. L. Brusseau, J. Artiola, R. M. Maier, and J. A Gandolfi, "Building a co-created citizen science program with gardeners neighboring a superfund site: The Gardenroots case study.", Int Public Health J, vol. 7, issue 1, 2015 Jan. PubMed PMCID: PMC4420190  PMID: 25954473

2014

Ramirez-Andreotta, M. D., M. L. Brusseau, J. F. Artiola, R. M. Maier, and J. A Gandolfi, "Environmental Research Translation: enhancing interactions with communities at contaminated sites.", Sci Total Environ, vol. 497-498, pp. 651-64, 2014 Nov 1. PubMed PMCID: PMC4186773  PMID: 25173762
Zhou, X., X. Sun, C. Mobarak, J. A Gandolfi, S. W. Burchiel, L. G. Hudson, and K. Jian Liu, "Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteins.", Chem Res Toxicol, vol. 27, issue 4, pp. 690-8, 2014 Apr 21. PubMed PMCID: PMC3998772  PMID: 24611629
Burchiel, S. W., F. T. Lauer, E. J. Beswick, J. A Gandolfi, F. Parvez, K. Jian Liu, and L. G. Hudson, "Differential susceptibility of human peripheral blood T cells to suppression by environmental levels of sodium arsenite and monomethylarsonous acid.", PLoS One, vol. 9, issue 10, pp. e109192, 2014. PubMed PMCID: PMC4182801  PMID: 25271956