Genomics
Facility Core
To consolidate resources and expertise in
order to minimize cost and effort to health science researchers who want
to use microarrays.
The
analytical power of microarray technology has been successfully
applied throughout health science research. From basic toxicity
studies to new drug development, microarrays are being used to
explore the transcriptional responses of a wide array of biological
systems.
The
Bioinformatics Facility Core consists of four members, who are
housed in the Arizona Cancer Center.
Recent
publications by members of the core. For a complete list of publications
click here.
Zheng,
X. H., Watts, G. S., Vaught, S., and Gandolfi, A. J. (2003).
Low-level arsenite induced gene expression in HEK293 cells.
Toxicology 187, 39-48.
Chauhan
S., Pandey R., Way J.F., Sroka T.C., Demetriou M.C., Kunz
S., Cress A.E., Mount D.W., and Miesfeld R.L. (2003) Androgen
regulation of the human FERM domain encoding gene EHM2 in
a cell model of steroid-induced differentiation. Biochem.
Biophys. Res. Commun., 310(2):421-32.
Watts
G.S., Oshiro M.M., Junk D.J., Wozniak R.J., Watterson S.,
Domann F.E., and Futscher B.W. (2003) The acetyltransferase
p300/CBP-associated factor (PCAF) is a p53 target gene in
breast tumor cells. Neoplasia, In Press.
Huang
S., Watts G.S., Su H, Marshall B., Smith B., and Chen H.
(2003). Learning genetic pathways using Bayesian networks
and qualitative probabilistic networks. Bioinformatics, Submitted.
Ignatenko
N.A., Zhang H., Watts G.S., Skovan B.A., Stringer D.E., and
Gerner E.W. (2003). The chemopreventative agent a-difluoromethylornithine
blocks k-ras dependent tumor formation and specific gene
expression in Caco-2 cells. Mol. Carcinogen., Submitted.
Links
to prices and online request form for Genomics services:
Southwest
Environmental Health Sciences Center
University of Arizona College of Pharmacy, Room 244
PO Box 210207, Tucson, AZ, USA 85721-0207 swehsc-info@pharmacy.arizona.edu
520-626-5594
520-626-6944(FAX)