CENTER INTEGRATION RESOURCE (aka The CIR)

Dr. Walt Klimecki, CIR leader and IHS Co-Director, discusses the role of the Center Integration Resource
in boosting translational research at the SWEHSC.

 

 

 

FIRST THINGS FIRST

The Center Integration Resource ensures that translational research is maximally integrated within SWEHSC, including its facility cores, and translational research resources available within the greater University of Arizona community. By doing this CIR minimizes the inefficiencies that occur when available, beneficial resources are ignored.

 The CIR is a hub for the multidisciplinary resources of SWEHSC and the University of Arizona. CIR members present a wide range of expertise to assist SWEHSC translational researchers in experimental models and specialized surgical and measurement procedures. Experts share strategic, as well as technical “nuts and bolts” expertise with SWEHSC investigators.  Assistance is available for both biological as well as chemical analyses. Many CIR members are affiliated with broader research resources at the U. of Arizona that could benefit SWEHSC investigators. 

Expertise in the CIR includes these areas:

Genetics/DNA Sequencing/Genotyping

  • DNA sequence analysis, copy number analysis, Genotyping, GWAS analysis, Next-Gen Sequencing

Epigenetics Analysis

  • Technology platforms for analysis of epigenetic marks, focused and genome-wide

Genomic Gene Expression/Microarray

  • mRNA analysis, Microarray, Next Gen mRNA analysis, Data analysis

Experimental Models

  • Locally available experimental models

Chemical Analysis/Methods Development

  • Chemical analysis of environmental and biological samples

Community Outreach and Education

  • Translating research findings to target audiences
  • Community Based Participatory Research

 

PROJECT CONSULT : The IHS Pathway to Project Support

The CIR has developed a structured approach to providing assistance for projects receiving subsidized support, to ensure that the best delivery of support results in successful research outcomes.  To learn more about the Project Consult process click here.

 

HOW DO I GET HSR HELP?

Option 1:  If you want financial support for your project you must complete a Project Assistance Form

Option 2:  You can contact CIR leader Dr. Walt Klimecki by calling (520) 626-7470 or click here to send him an email

Option 3:  If you know the specific area in which you need help, you can access our CIR expertise tableto be linked to the SWEHSC expert in that area.

 

LEADERSHIPWalter Klimecki, DVM, Ph.D.

The CIR is led by Walter Klimecki, DVM, Ph.D.  Dr. Klimecki is an Assistant Professor of Pharmacology and Toxicology, with joint appointments in the College of Medicine and College of Public Health. 
He provides expertise in high-throughput genetic analyses and experiences with studying susceptible, at-risk populations to RFG1 and the SWEHSC. His first position at the University of Arizona was to pursue studies in the genetics of individual susceptibility to asthma, building and managing a high throughput genetic analysis laboratory as the Principal Investigator of two components of an NHLBI-funded Programs in Genomics Applications award. During that time he developed collaborations with the University of Arizona Superfund program, studying individual variability in genes responsible for the metabolism of inorganic arsenic in exposed populations in Mexico and continued his translational focus in the determinants of arsenic metabolism variability (a well established disease risk factor), as well as variability in susceptibility to arsenic-induced immunosuppression among exposed people.

 

 

CIR Members and Their Expertise - click on member name to contact

CIR Members Expertise