Ting Wang

Mechanisms of particulate matter-mediated cardiopulmonary toxicity in heart failure

This Pilot Project was used to support research to determine the biological mechanisms underlying cardiac toxicity due to the exposure to particulate matter (PM). Prior data from this lab suggested that PM-mediated cardiac toxicity involves pollution-induced inflammatory lung injury, increased lung vascular leakage, and the subsequent release of oxidative stress and inflammatory mediators that result in hypoxemia and increased blood coagulability.

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