Arsenic is a ubiquitous environmental toxicant, found in high concentrations in water worldwide; more than 150 million people live in areas with the arsenic content significantly higher than the WHO and USEPA recommended guidelines (10 ppb).The lung is a target organ for arsenic toxicity.
The overall objective of this research was to determine the mechanism by which arsenic alters Club (formerly Clara) cell protein (CC16) production and the role of induced CC16 in altering lung structure and function following early life exposure to arsenic. Drs. Lantz and Chen recently identified a set of proteins, mostly markers of systemic inflammation, whose serum levels were strongly related to exposure to cigarette smoking and impaired lung function.
The University of Arizona College of Pharmacy announced a promotion:
Yin Chen, PhD, a faculty member in the UA College of Pharmacy Department of
Pharmacology and Toxicology, will be promoted from assistant professor to associate
Yin Chen, PhD, assistant professor in the College of Pharmacy Department of Pharmacology and Toxicology, is co-principal