RFG3

Oxidative Stress

Mechanisms of cell death are usually classified into two pathways, apoptosis and oncosis/necrosis. Necrosis/oncosis typically occurs in response to toxic injury, including that induced by chemical exposure and reactive oxygen species (ROS). In contrast to apoptosis, oncosis is characterized by cell and organelle swelling that eventually leads to the loss of plasma membrane integrity. The generation of ROS has been implicated in the pathogenesis of renal ischemia/reperfusion injury, and many other pathological conditions.

Research

The SWEHSC plays an important role in stimulating collaborative interactions among researchers. This is evidenced by a significant number of new, funded research projects, as well as a notable number of planned initiatives involving collaborations. The SWEHSC promotes and enhances collaborative research within and between the members through Research Focus Groups.

The themes of the three Research Focus Groups are seen below:

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