Dr. Bernard Futscher One of Three Appointed to Breast Cancer Chairs at Arizona Cancer Center

A $5 million gift from the late Fenton L. Maynard also will provide breast cancer research endowments.

As highlighted in the UA News article by Sarah Hammond,

"Bernard W. Futscher, a professor of pharmacology and toxicology in the UA College of Pharmacy and scientific director of the Arizona Cancer Center's genomics shared service. Futscher's longstanding cancer research interest is in the area epigenetics - the study of the control of cell identity and behavior. Futscher's lab was the first to identify epigenetic inactivation of the breast cancer gene, BRCA1, as a common event in sporadic human breast cancer and its laboratory correlates.

Subsequent research by the Futscher lab demonstrated that normal epigenetic mechanisms can control gene activity in specific cell types and disruption of these mechanisms occurs early in the development of human breast cancer. Dr. Futscher's current research applies the knowledge of breast cancer epigenetics to the rational development of therapeutic interventions and biomarkers for disease prognostication."

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