Urine arsenic concentrations and species excretion patterns in American Indian communities over a 10-year period: the Strong Heart Study

Author Name: 
Navas-Acien, A., Umans, J. G., Howard, B. V., et al.
Publication Date: 
Friday, January 9, 2009
Background: Arsenic exposure in drinking water disproportionately affects small communities in some U.S. regions, including American Indian communities. In U.S. adults with no seafood intake, median total urine arsenic is 3.4 μg/L. oBjective: We evaluated arsenic exposure and excretion patterns using urine samples collected over 10 years in a random sample of American Indians from Arizona, Oklahoma, and North and South Dakota who participated in a cohort study from 1989 to 1999. conclusions: This study found low to moderate inorganic arsenic exposure and confirmed long­ term constancy in arsenic exposure and urine excretion patterns in American Indians from three U.S. regions over a 10­year period. Our findings support the feasibility of analyzing arsenic species in large population­based studies with stored urine samples. (from abstract)