Lawrence Mandarino

Research Focus Group Membership: 
Research Focus Group 1
  • PhD: Physical Anthropology, Arizona State University
  • MA: Physical Antropology, Arizona State University
  • BA: Mathematics, Arizona State University
College Affiliations: 

College of Medicine
College of Pharmacy

Research Interests: 

Mechanisms of insulin action in skeletal muscle, pathogenesis of type 2 diabetes mellitus, mass spectrometry based proteomics, protein structure and function., cell signaling, post translational modifications of proteins.

Environmental Health Research & Expertise: 

Dr. Mandarino’s research has been supported by the National Institutes of Health for more than 25 years. Currently, he is principal investigator on two studies with grant funding totaling more than $5 million. His research interests include the mechanisms of insulin resistance in skeletal muscle and liver and the mechanisms of fatty liver development. His research is aimed at providing new targets for treating insulin resistance syndrome – sometimes referred to as metabolic syndrome – which increases the risk of obesity, type 2 diabetes, cardiovascular disease and other cardiometabolic conditions, all areas of special concern in the Latino population. In 2009, he received the American Diabetes Association’s Cure Award, presented to a key researcher who is engaged in basic or clinical research focusing on the treatment, cure or prevention of diabetes and its complications.